EECP Can Improve Exercise capacity in Chronic Heart Failure patients 體外反搏治療有效提高慢性心臟衰竭(CHF)患者的 運動能力

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EECP Can Improve Exercise capacity in Chronic Heart Failure patients


This meta-analysis aimed to synthesize randomized controlled trials to evaluate the effects of enhanced external counterpulsation (EECP) on exercise capacity and quality of life in patients with chronic heart failure (CHF).


Both English and Chinese databases were searched from their inception to June 30, 2020 (PubMed, EMBASE, Cochrane Library, CINAHL (EBSCO), Web of Science for English publications and Chinese Biomedical Database, China National Knowledge Infrastructure, Wanfang Data for Chinese publication). Titles, abstracts, and full-text articles were screened against study inclusion criteria: randomized controlled trials studying EECP intervention for patients with CHF. The meta-analysis was conducted with Revman 5.3 or STATA 16.0.


Eight randomized controlled trials were included. EECP induced significant improvement in 6-min walking distance (WMD=84.79 m; 95% CI, 47.64 to 121.95; P < .00001). Moreover, EECP was beneficial for left ventricular ejection fraction (SMD = 0.64; 95% CI,0.29 to 1.00; P = .0004), and N-terminal pro brain natriuretic peptide (SMD = -0.61; 95%CI, -1.20 to -0.01; P = 0.04). However, compared with the control groups, EECP did not significantly reduce the Minnesota Living with Heart Failure Questionnaire scores(WMD, -9.28; 95% CI, -19.30 to 0.75; P = 0.07).


Despite heterogeneity and risk of bias, this meta-analysis confirms that EECP can improve exercise capacity in CHF patients, especially the elderly. However, the evidence that EECP improves the quality of life in patients with CHF is still insufficient. More and larger well-designed randomized controlled trials are still warranted.

增強體外反搏對慢性心力衰竭患者 運動能力 和生活品質的影響: 薈萃分析


本分析旨在綜合評估體外反搏(EECP)對慢性心臟衰竭(CHF)患者 運動能力 和生活品質的影響的薈萃分析。


檢索從 2020 年 6 月 30 日的中英文資料庫(英文出版物檢索 PubMed、EMBASE、Cochrane Library、CINAHL (EBSCO)、Web of Science,中文出版物檢索中國生物醫學資料庫、中國國家知識基礎設施、萬方資料)開始。根據研究納入標準對文章的標題、摘要和全文進行了篩選:研究對 CHF 患者進行 EECP 幹預的隨機對照試驗。使用 Revman 5.3 或 STATA 16.0 進行分析。


共納入 8 項隨機對照試驗。EECP 顯著改善了 6 分鐘明步行距離。此外,EECP 改善了左心室射血分數和 N 末端腦鈉。 然而,與對照組相比,EECP 並未顯著降低明尼蘇達心衰患者生活問卷評分。