EECP Decreases Blood Pressure; Effects Did Not Persist at 12 Month Follow Up 體外反搏減低血壓,但成效未能長久維持

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EECP Decreases Blood Pressure; Effects Did Not Persist at 12 Month Follow Up

OBJECTIVE:

Enhanced external counterpulsation (EECP) is a non-invasive technique that has been shown to reduce the frequency and severity of angina pectoris. Little is known how EECP affects the blood pressure.

METHODS:

153 patients with refractory angina were treated with either EECP or retained on their pharmacological treatment (reference group). Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) and heart rate were measured pre- and post-treatment and at 12 months follow-up.

RESULTS:

EECP treatment altered the blood pressure in patients with refractory angina pectoris. A decrease in the blood pressure was more common in the EECP group compared with the reference group. In the reference group, an increase in the blood pressure was more common. A correlation between a decrease in blood pressure after EECP treatment and a higher baseline MAP, SBP and DBP was seen. No such correlation was seen in the reference group. The blood pressure response did not persist at 12 months follow-up.

CONCLUSION:

EECP treatment affects the blood pressure in patients with refractory angina pectoris. The decreased blood pressure may be a result of an improved exercise capacity, an improved endothelial function and vasoreactivity in general.

「體外反搏對難治性心絞痛患者的血壓影響」

目標

體外反搏(EECP)是一種非侵入性技術,已被證明可以減少心絞痛的頻率和嚴重程度。可是,我們對其於血壓上之影響的認識並不大。

方法

對153名難治性心絞痛患者進行了EECP治療,或者繼續使用他們的藥物治療(參考組)。測量了治療前後和12個月後的收縮壓(SBP)、舒張壓(DBP)、平均動脈壓(MAP)和心率。

結果

EECP治療改變了難治性心絞痛患者的血壓。與參考組相比,EECP組的 血壓下降 更為常見。在參考組中,血壓增加更常見。發現EECP治療後 血壓下降 與基線MAP、SBP和DBP較高呈正相關。在參考組中沒有觀察到這種相關性。血壓反應在12個月的隨訪中沒有持續存在。

結論

EECP治療影響了難治性心絞痛患者的血壓。 血壓下降 可能是由於運動能力改善、內皮功能改善以及一般血管反應性改善所致。

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