EECP Increases Pulsatility to Human Blood Pressure 體外反搏治療增加人體血壓的 脈動性

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EECP Increases Pulsatility to Human Blood Pressure

Pulsatile blood flow plays an important role in maintaining normal vascular endothelial function. Quantitative measurement of pulsatility of human arterial blood pressure and the influence of enhanced external counterpulsation (EECP) on the pulsatility were investigated in this study. Eight healthy young male volunteers aged 22 to 35 were included. A 4F tip transducer catheter was inserted under local anaesthesia into the radial artery up to the aortic arch. Intraarterial blood pressure was recorded before and during EECP. Blood pulse pressure, pulsatility index (ratio of peak pressure to end diastolic pressure) and standard deviation of blood pressure in 5 cardiac cycle was calculated to evaluate the pulsatility of arterial blood pressure. The results showed that blood pulse pressure, pulsatility index and standard deviation of blood pressure were elevated from 47 +/- 5 mmHg, 1.64 +/- 0.11 and 13.6 +/- 1.5 mmHg to 77 +/- 3 mmHg, 2.46 +/- 0.25 and 19.3 +/- 2.2 mmHg before and during EECP respectively (P < 0.05). Decreasing of systolic pressure and increasing of diastolic pressure during counterpulsation were also observed. EECP gives an elevation of pulsatility to human blood pressure.

「體外反搏治療對人體血壓的 脈動性 效果」

脈動性 血流在維持正常血管內皮功能方面起著重要作用。本研究探討了人體動脈血壓的 脈動性 的定量測量以及體外反搏(EECP)對 脈動性 的影響。研究納入了8名健康的年輕男性志願者,年齡在22至35歲之間。在局部麻醉下,將4F壓力傳感器導管尖端插入橈動脈直至主動脈弓。記錄了EECP前和期間的動脈內血壓。計算了血脈搏壓、 脈動性 指數(峰壓與舒張末期壓的比值)和5個心律周期內的血壓標準差,以評估動脈血壓的 脈動性 。結果顯示,在EECP前,血脈搏壓、 脈動性 指數和血壓標準差分別從4、1.64和13.6mmHg增加到EECP期間的77  mmHg、2.46和19.3 mmHg。還觀察到反搏期間收縮壓的降低和舒張壓的增加。EECP使人體血壓的 脈動性 增加。