Effects of EECP on Erectile Dysfunction are Influenced by Risk Factors 體外反搏治療對勃起功能障礙患者的成效受風險因素(如 吸煙 )影響

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Effects of EECP on Erectile Dysfunction are Influenced by Risk Factors

INTRODUCTION:

Recently it has been demonstrated that enhanced external counterpulsation (EECP) could improve erectile dysfunction (ED) in patients with refractory ischemic heart disease (IHD).

AIM:

To assess the effect of risk factors on the efficacy and the satisfaction rate of EECP in patients with coronary artery disease (CAD)-associated ED.

MAIN OUTCOME MEASURES:

To assess the effect of risk factors on EECP efficacy and satisfaction rate, we compared the pre- and post-EECP responses to erectile function domain, Q3, and Q4 in patients with and without risk factors. Overall satisfaction and global efficacy question (GEQ) were also assessed.

METHODS:

A total of 44 male consecutive patients with intractable angina caused by coronary insufficiency which cannot be controlled by conventional therapy were enrolled in this study. Patients were screened and followed up for ED using erectile function domain of the International Index for Erectile Function. A thorough sexual, medical, and psychosocial history was taken from all patients.

RESULTS:

All patients had severe diffuse triple vessels disease. They all had class III or IV angina. They were receiving the maximal antianginal pharmacotherapy. The mean age +/- SD was 57.1 +/- 5.6 years. Of the patients, 63.9% were below 60 years, and 86.4% were current or ex-smokers. There were significant differences between pre- and post-EECP regarding erectile function domain, Q3, and Q4. The sociodemographic variables were not significantly different among the studies groups and had not affected the GEQ or overall satisfaction. Overall satisfaction and GEQ were negatively influenced by smoking and presence of more than two risk factors. However, diabetes, hypertension, dyslipidemia, myocardial infraction, and obesity have not had such effects.

CONCLUSIONS:

The efficacy and satisfaction rate of EECP in patients with CAD-associated ED were negatively influenced by presence of risk factors; however, the global efficacy and the overall patients’ satisfaction were encouraging.

「冠狀動脈疾病相關勃起功能障礙患者的增強體外反搏。第一部分:風險因素的影響」

簡介

最近的研究表明,體外反搏治療(EECP)可以改善難治性缺血性心臟病(IHD)患者的勃起功能障礙(ED)。

目的

評估風險因素對EECP治療冠狀動脈疾病(CAD)相關ED患者的療效和滿意度的影響。

主要結果指標

為了評估風險因素對EECP療效和滿意度的影響,我們比較了有和無風險因素患者在EECP治療前後對勃起功能領域、Q3和Q4的反應。還評估了整體滿意度和整體療效問題(GEQ)。

方法

本研究共納入 44 名因冠狀動脈供血不足引起的頑固性心絞痛且常規治療無法控制的男性患者。我們使用國際勃起功能指數的勃起功能領域(erectile function domain),篩查和隨訪患者的勃起功能障礙。我們亦從所有患者中獲取了他們詳盡的性行為、醫學和心理病史。

結果

所有患者的三條冠狀動脈都有嚴重心血管毛病。他們全部為III級或IV級心絞痛。他們正接受最大劑量的抗心絞痛藥物治療。其中63.9%的患者年齡在60歲以下,86.4%是目前或曾經 吸煙 者。在勃起功能領域、Q3和Q4方面,EECP治療前後存在顯著差異。在研究組中,社會人口變量在GEQ或整體滿意度上沒有顯著差異。整體滿意度和GEQ受 吸煙 和存在兩個以上風險因素的影響而呈負面影響。然而,糖尿病、高血壓、血脂異常、心肌梗塞和肥胖對此沒有產生類似的影響。

結論

CAD相關ED患者的EECP療效和滿意度受風險因素的影響呈負面影響;然而,整體療效和患者整體滿意度是令人鼓舞的。

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